A study published in the journal Neurology, estimates that people who use the 4 DMD medications for a decade would get a modest health benefit for the money. My thought was I should be taking something rather than nothing. The statistics showed, at least they convinced me a scared newly diagnosed patient, that one was better off taking something rather than nothing. I have been through all 4 for the last 11 years, starting with Betaseron because it had been in the market the longest, and lasted for about three years before switching to Rebif.
I did not tolerate the increased frequency of the inteferons that came with Rebif. I did, however, give Rebif a year to see if my body would adapt and reduce the number of side effects. But the constant muscle aches and decreased mobility, I switched to Copaxone and was amazed at how well my body tolerated the glatiramer. I was happy for the change and energized. But after five years, I stopped noticing any benefit. For the last two years I have been trying to live a less stressful life, eating more healthy foods (more regular exercise is next on my list) and have not noticed any considerable difference from being on a DMD.