Archive for 'Drugs'
Tovaxin
Opexa Therapeutics, Inc. announced results from further analysis of the double-blind, placebo-controlled, 52-week Phase IIb TERMS clinical study of 150 patients with Relapsing Remitting MS (RRMS). This analysis evaluated patients with an annualized relapse rate of one or greater at study entry (ARR≥1). More than 83% of the Tovaxin-treated group (n=85) remained relapse free at [...]
Full StoryInflammation and paralysis reversed with common blood pressure medication
Conventional blood pressure medication can treat inflammation in an animal model mimicking multiple sclerosis (MS). This discovery was made by Dr. Michael Platten, head consultant at the department of Neurooncology at Heidelberg University Hospital and head of the Helmholtz Experimental Neuroimmunology Junior Research Group on at the German Cancer Research Center and his team in [...]
Full StoryMS in mice reversed with one shot
An experimental treatment has yeilded incredible results in mice with a disease similar to multiple sclerosis.
The new treatment, named GIFT15 puts MS into remission by suppressing the immune response. This means it might also be effective against other autoimmune disorders like Crohn’s disease, lupus and arthritis, the researchers said, and could theoretically also control immune [...]
Diabetes Drug May Help Treat MS
U.S. medical researchers say they’ve found a drug used to treat diabetes shows protective effects in the brains of some multiple sclerosis patients.
Researchers at the University of Illinois-Chicago College of Medicine say they conducted a small, double-blind clinical trial involving patients with relapsing remitting multiple sclerosis. The patients were assigned to take pioglitazone — a [...]
Prediction: Three to Five Years for MS wonder drug
Dr. Richard Shubin from the Casa Colina’s Multiple Sclerosis Center in Pomona explains the latest advances in new medications:
In a cell biology lab at UC Riverside, researchers look at the four screens of a flow cytometer, a sophisticated instrument that searches for fluorescent labeled reactions inside cells.
Some cell activities will fluoresce green, red, yellow [...]
BioVista drug BVA-101 shows promise
Pharmaceutical company BioVista announced positive results from their pre-clinical trials for the drug BVA-101. According to their press release, the results were achieved against Experimental Allergic Encephalomyelitis which I am guessing is an ms-like disease in animals. I have written to Dr. Aris Persidis, president of Biovista seeking more information.BioVista is headquartered in Charlottesville, [...]
Full StoryPossible Solution for Negative Effects of Tysabri
You may know of the rare but potential deadly side effect of Tysabri. Biogen is testing a malaria pill used in treating progressive multifocal leukoencephalopathy (PML), the brain infection that has been tied to use of Tysabri.
Helen Yates, Chief Executive of the Multiple Sclerosis Resource Centre (MSRC) said: “We truly hope that the research leads [...]
Experimental Drug Improves Mobility
Some MS patients have seen improved mobility treatment with Fampridine. The medication can improve transmission of signals in the central nervous systems.
The experimental drug fampridine (4-aminopyridine) improves walking ability in some individuals with multiple sclerosis (MS). That is the conclusion of a multi-center Phase 3 clinical trial, the results of which were published February 26 [...]
Oral Medication My Reduce Lesions
There is hope that this new medicine will replace daily injections. Laquinimod has been in the pipeline for a while and study results have been out for a few months.
“These latest data show the rapid onset and sustainability of laquinimod efficacy in MS patients,” said Giancarlo Comi, M.D., University Vita-Salute San Raffaele, Scientific Institute San [...]